Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | TYR | P14679 | 1/20 | 0.57 |
| ▸ | CA7 | P43166 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2219220 | 1.00 | CA12 (0.57) | CA12CA1CA2TYRCA7 | |
| SCHEMBL26690544 | 0.88 | RAB9A (0.50) | CA12CA1CA2TYRCA7 | |
| SCHEMBL15043513 | 0.87 | CA12 (0.55) | CA12CA1CA2TYRCA7 | |
| SCHEMBL22490430 | 0.85 | TRPM8 (0.57) | RAB9AMEN1NPC1POLBBLM | |
| SCHEMBL11748682 | 0.81 | GSK3B (0.51) | CA12CA1CA2TYRCA7 | |
| SCHEMBL1780164 | 0.81 | CA12 (0.49) | CA12CA1CA2TYRCA7 | |
| SCHEMBL1780168 | 0.81 | CA12 (0.49) | CA12CA1CA2TYRCA7 | |
| SCHEMBL1780162 | 0.81 | CA12 (0.49) | CA12CA1CA2TYRCA7 | |
| SCHEMBL1780166 | 0.81 | CA12 (0.49) | CA12CA1CA2TYRCA7 | |
| SCHEMBL1088759 | 0.81 | KMT2A (0.56) | CA12CA1CA2TYRCA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130317025-A1 | PDE-10 INHIBITORS | ENVIVO PHARMACEUTICALS INC (US) | 2013-11-28 | — | — | US | disclosed |
| US-8481532-B2 | PDE-10 inhibitors | ENVIVO PHARMACEUTICALS, INC. (US) | 2013-07-09 | — | — | US | disclosed |
| US-8481532-B2 | PDE-10 inhibitors | ENVIVO PHARMACEUTICALS, INC. (US) | 2013-07-09 | — | — | US | disclosed |
| US-8481532-B2 | PDE-10 inhibitors | ENVIVO PHARMACEUTICALS, INC. (US) | 2013-07-09 | — | — | US | disclosed |
| US-20110178083-A1 | PDE-10 INHIBITORS | ENVIVO PHARMACEUTICALS, INC. | 2011-07-21 | — | — | US | disclosed |
| US-20110178083-A1 | PDE-10 INHIBITORS | ENVIVO PHARMACEUTICALS, INC. | 2011-07-21 | — | — | US | disclosed |
| US-20110178083-A1 | PDE-10 INHIBITORS | ENVIVO PHARMACEUTICALS, INC. | 2011-07-21 | — | — | US | disclosed |
| WO-2010006130-A2 | PDE-10 INHIBITORS | ENVIVO PHARMACEUTICALS, INC. (US) | 2010-01-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130317025-A1 | PDE-10 INHIBITORS | PDE12, PDE10A, PDE2A | CA12 2667/4885CA1 710/4885CA2 1828/4885 |
| US-20110178083-A1 | PDE-10 INHIBITORS | PDE12, PDE10A, PDE2A | CA12 2667/4885CA1 710/4885CA2 1828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.