Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | P4HB | P07237 | 1/20 | 0.52 |
| ▸ | PDIA4 | P13667 | 1/20 | 0.52 |
| ▸ | PDIA3 | P30101 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA4 | P22748 | 2/20 | 0.51 |
| ▸ | CA5A | P35218 | 2/20 | 0.51 |
| ▸ | CA7 | P43166 | 2/20 | 0.51 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22194028 | 1.00 | TSHR (0.58) | TSHRCYP2D6THRBHSD17B10P4HB | |
| SCHEMBL24120515 | 1.00 | TSHR (0.58) | TSHRCYP2D6THRBHSD17B10P4HB | |
| SCHEMBL20633976 | 0.87 | P4HB (0.61) | TSHRCYP2D6THRBHSD17B10P4HB | |
| SCHEMBL8946122 | 0.87 | TSHR (0.59) | TSHRCYP2D6THRBHSD17B10P4HB | |
| SCHEMBL7744449 | 0.87 | TSHR (0.59) | TSHRCYP2D6THRBHSD17B10P4HB | |
| SCHEMBL23457428 | 0.86 | TSHR (0.58) | TSHRCYP2D6THRBHSD17B10P4HB | |
| SCHEMBL23479749 | 0.86 | TSHR (0.58) | TSHRCYP2D6THRBHSD17B10P4HB | |
| SCHEMBL22193707 | 0.86 | TSHR (0.58) | TSHRCYP2D6THRBHSD17B10P4HB | |
| SCHEMBL23457384 | 0.86 | TSHR (0.58) | TSHRCYP2D6THRBHSD17B10P4HB | |
| SCHEMBL14353401 | 0.86 | TSHR (0.58) | TSHRCYP2D6THRBHSD17B10P4HB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020141460-A2 | COMPOUNDS COMPRISING CLEAVABLE LINKER AND USES THEREOF | INTOCELL, INC. (KR) | 2020-07-09 | — | — | WO | disclosed |