Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | P4HB | P07237 | 1/20 | 0.53 |
| ▸ | PDIA4 | P13667 | 1/20 | 0.53 |
| ▸ | PDIA3 | P30101 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9122366 | 0.90 | TSHR (0.56) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL20635286 | 0.88 | TSHR (0.57) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL26263822 | 0.88 | TSHR (0.51) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL20633976 | 0.88 | P4HB (0.61) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL8946122 | 0.88 | TSHR (0.59) | TSHRCYP2D6THRBHSD17B10P4HB | |
| SCHEMBL24120515 | 0.87 | TSHR (0.58) | TSHRCA12CA1CA2CYP2D6 | |
| SCHEMBL23479749 | 0.87 | TSHR (0.58) | TSHRCA12CA1CA2CYP2D6 | |
| SCHEMBL22194037 | 0.87 | TSHR (0.58) | TSHRCA12CA1CA2CYP2D6 | |
| SCHEMBL23457384 | 0.87 | TSHR (0.58) | TSHRCA12CA1CA2CYP2D6 | |
| SCHEMBL22193707 | 0.87 | TSHR (0.58) | TSHRCA12CA1CA2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001010877-A1 | C-GLYCOSIDE ANALOGS AND METHODS FOR THEIR PREPARATION AND USE | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2001-02-15 | — | — | WO | disclosed |