Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | TOP1 | P11387 | 3/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | JAK1 | P23458 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14903561 | 0.92 | TSHR (0.67) | TSHRKDM4EALDH1A1RAB9AGAA | |
| SCHEMBL10767069 | 0.81 | TSHR (0.66) | TSHRKDM4EALDH1A1RAB9AGAA | |
| SCHEMBL8679604 | 0.81 | TSHR (0.53) | TSHRKDM4EALDH1A1RAB9AGAA | |
| SCHEMBL6550416 | 0.80 | TSHR (0.75) | TSHRKDM4EALDH1A1RAB9AGAA | |
| SCHEMBL30307376 | 0.79 | CYP1A2 (0.63) | TSHRALDH1A1GAAMEN1CYP3A4 | |
| SCHEMBL547153 | 0.79 | CYP1A2 (0.63) | TSHRALDH1A1GAAMEN1CYP3A4 | |
| SCHEMBL30154503 | 0.78 | TSHR (1.00) | TSHRKDM4EALDH1A1RAB9AGAA | |
| SCHEMBL640263 | 0.78 | TSHR (1.00) | TSHRKDM4EALDH1A1RAB9AGAA | |
| SCHEMBL2219672 | 0.78 | GAA (0.62) | TSHRKDM4EALDH1A1RAB9AGAA | |
| SCHEMBL8679606 | 0.78 | TSHR (0.62) | TSHRKDM4EALDH1A1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130053594-A1 | METHODS OF MAKING SELF-HEALING POLYMER AND GEL COMPOSITIONS | THE UNIVERSITY OF CHICAGO (US) | 2013-02-28 | — | — | US | disclosed |
| WO-2011084710-A1 | METHODS OF MAKING SELF-HEALING POLYMER AND GEL COMPOSITIONS | THE UNIVERSITY OF CHICAGO (US) | 2011-07-14 | — | — | WO | disclosed |
| EP-0232679-B1 | SYNTHETIC ORGANIC POLYMERS FOR THE SELECTIVE FLOCCULATION OF TITANIUM AND IRON ORES | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 1990-07-25 | — | — | EP | disclosed |
| US-4698171-A | Synthetic organic polymers for the selective flocculation of titanium and iron ores | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 1987-10-06 | — | — | US | disclosed |
| EP-0232679-A1 | Synthetic organic polymers for the selective flocculation of titanium and iron ores | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 1987-08-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130053594-A1 | METHODS OF MAKING SELF-HEALING POLYMER AND GEL COMPOSITIONS | PCNA, PUF60, PPIG | TSHR 4860/4885KDM4E 4324/4885ALDH1A1 3132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.