SCHEMBL22197216

SCHEMBL22197216

Oc1ccc(C2(c3ccccc3)c3cc(Br)ccc3-c3ccc(Br)cc32)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 2/20 0.44
OPRM1 P35372 1/20 0.43
OPRD1 P41143 1/20 0.43
ALOX15 P16050 2/20 0.39
ESR1 P03372 3/20 0.38
ESR2 Q92731 3/20 0.38
CHRM2 P08172 1/20 0.38
ADORA3 P0DMS8 1/20 0.38
KCNH2 Q12809 1/20 0.38
MEN1 O00255 2/20 0.37
LMNA P02545 2/20 0.37
MAPT P10636 2/20 0.37
KMT2A Q03164 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
PTPRC P08575 1/20 0.37
KDM4E B2RXH2 1/20 0.37
OPRK1 P41145 1/20 0.37
PDE4D Q08499 3/20 0.36
BCL2 P10415 1/20 0.36
MCL1 Q07820 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21793191 0.95 PDK2 (0.48) PDK2OPRM1OPRD1ALOX15ESR1
SCHEMBL1308895 0.93 ALOX15 (0.44) PDK2OPRM1OPRD1ALOX15ESR1
SCHEMBL3813379 0.92 PDK2 (0.50) PDK2OPRM1OPRD1ALOX15ESR1
SCHEMBL29523761 0.92 PDK2 (0.50) PDK2OPRM1OPRD1ALOX15ESR1
SCHEMBL29540116 0.89 PDK2 (0.47) PDK2OPRM1OPRD1MEN1LMNA
SCHEMBL1307887 0.89 PDK2 (0.47) PDK2OPRM1OPRD1MEN1LMNA
SCHEMBL24730435 0.86 MEN1 (0.43) PDK2OPRM1OPRD1ESR1ESR2
SCHEMBL12669173 0.85 ACHE (0.42) PDK2ALOX15ESR1ESR2PDE4D
SCHEMBL21793378 0.85 ESR1 (0.49) PDK2OPRM1OPRD1ALOX15ESR1
SCHEMBL29524532 0.85 ESR1 (0.49) PDK2OPRM1OPRD1ALOX15ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11472901-B2 Polymer, coating composition comprising same, and organic light-emitting device using same LG CHEM, LTD. 2022-10-18 US disclosed
US-11374175-B2 Polymer, coating composition comprising same, and organic light-emitting device using same LG CHEM, LTD. 2022-06-28 US disclosed
US-20200239610-A1 Polymer, Coating Composition Comprising Same, and Organic Light-Emitting Device Using Same LG CHEM, LTD. (KR) 2020-07-30 US disclosed
US-20200235301-A1 Polymer, Coating Composition Comprising Same, and Organic Light-Emitting Device Using Same LG CHEM, LTD. (KR) 2020-07-23 US disclosed
EP-3677602-A1 POLYMER, COATING COMPOSITION COMPRISING SAME, AND ORGANIC LIGHT-EMITTING DEVICE USING SAME LG CHEM, LTD. (KR) 2020-07-08 EP disclosed
EP-3677606-A1 POLYMER, COATING COMPOSITION COMPRISING SAME, AND ORGANIC LIGHT-EMITTING DEVICE USING SAME LG CHEM, LTD. (KR) 2020-07-08 EP disclosed