Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 3/20 | 0.37 |
| ▸ | ACACA | Q13085 | 3/20 | 0.37 |
| ▸ | L3MBTL3 | Q96JM7 | 7/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.37 |
| ▸ | MBTD1 | Q05BQ5 | 4/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.37 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3764738 | 0.89 | EPHX2 (0.43) | EPHX2EPHX1CYP1A2TDP1 | |
| SCHEMBL14239713 | 0.79 | CHRM1 (0.46) | CHRM1LMNAACACBACACAL3MBTL3 | |
| SCHEMBL22198010 | 0.79 | HPGD (0.50) | CHRM1L3MBTL1EPHX1 | |
| SCHEMBL15450906 | 0.78 | KDM4E (0.51) | CHRM1LMNAL3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL3938492 | 0.77 | L3MBTL3 (0.56) | L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4 | |
| SCHEMBL13207179 | 0.77 | L3MBTL3 (0.56) | L3MBTL3L3MBTL1MBTD1EPHX2EPHX1 | |
| SCHEMBL4759350 | 0.77 | CYP2D6 (0.31) | — | |
| SCHEMBL22878225 | 0.77 | CHRM1 (0.41) | CHRM1LMNAL3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL17284621 | 0.77 | CHRM1 (0.44) | CHRM1LMNAL3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL22198006 | 0.76 | ALDH1A1 (0.40) | L3MBTL3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142228-A1 | ANDROGEN RECEPTOR PROTEIN DEGRADERS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2020-07-09 | — | — | WO | disclosed |