Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 19/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 15/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 13/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | TSPO | P30536 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18240372 | 0.79 | CHRM3 (0.50) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL826276 | 0.77 | CHRM3 (0.49) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL2289504 | 0.73 | CHRM3 (0.46) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL73891 | 0.72 | CHRM3 (0.43) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL73892 | 0.72 | DAO (0.45) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL982657 | 0.72 | CHRM3 (0.45) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL2829164 | 0.71 | CHRM3 (0.41) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL16053656 | 0.71 | CHRM3 (0.47) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| Bromide SCHEMBL16713401 | 0.71 | DAO (0.43) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| Fluoride SCHEMBL14940050 | 0.71 | DAO (0.43) | CHRM3CHRM2CHRM1CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200215051-A1 | NEBULIZATION COMPOSITION COMPRISING TIOTROPIUM AND INDACATEROL | GLENMARK SPECIALTY S.A. (CH) | 2020-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200215051-A1 | NEBULIZATION COMPOSITION COMPRISING TIOTROPIUM AND INDACATEROL | IL5, IL17A, CFTR | CHRM3 72/4885CHRM2 296/4885CHRM1 487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.