Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 17/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 15/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 13/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.39 |
| ▸ | HRH1 | P35367 | 3/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.39 |
| ▸ | TACR1 | P25103 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14142347 | 0.79 | PDPK1 (0.46) | CHRM3CHRM2CHRM1LMNAALDH1A1 | |
| SCHEMBL7082002 | 0.76 | HPGD (0.43) | CHRM3CHRM2CHRM1HPGDALDH1A1 | |
| SCHEMBL931372 | 0.76 | CHRM2 (0.39) | CHRM3CHRM2CHRM1ALDH1A1NPC1 | |
| SCHEMBL7081055 | 0.76 | L3MBTL1 (0.34) | CHRM3HPGDLMNAALDH1A1NFKB1 | |
| SCHEMBL7085430 | 0.76 | NPC1 (0.43) | CHRM3CHRM2CHRM1HPGDLMNA | |
| SCHEMBL7081056 | 0.75 | MEN1 (0.36) | CHRM3CHRM2CHRM1LMNAALDH1A1 | |
| SCHEMBL14142466 | 0.74 | CHRM3 (0.34) | CHRM3CHRM2CHRM1LMNAALDH1A1 | |
| Bromomethane SCHEMBL7086772 | 0.74 | NPC1 (0.41) | CHRM3CHRM2CHRM1HPGDLMNA | |
| SCHEMBL7082997 | 0.74 | CES2 (0.43) | CHRM3CHRM2CHRM1ALDH1A1NFKB1 | |
| SCHEMBL2289504 | 0.74 | CHRM3 (0.46) | CHRM3CHRM2CHRM1ALDH1A1CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8563731-B2 | Mesylate salt of 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]jamino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one as agonist of the β2 adrenergic receptor | ALMIRALL, S.A. (ES) | 2013-10-22 | — | — | US | claimed |
| EP-1126922-B1 | PRESSURE-COMPENSATING DEVICE FOR A DUAL CONTAINER | BOEHRINGER INGELHEIM INT (DE) | 2006-04-26 | — | — | EP | claimed |
| US-6988496-B1 | Cartridge for a liquid | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-01-24 | — | — | US | claimed |
| EP-1156769-B1 | CARTRIDGE FOR A LIQUID | BOEHRINGER INGELHEIM INT (DE) | 2004-09-29 | — | — | EP | claimed |
| EP-1058657-B1 | USE OF A CONTAINER FOR A MEDICINAL LIQUID IN A SPRAYING DEVICE | BOEHRINGER INGELHEIM INT (DE) | 2003-05-28 | — | — | EP | claimed |
| US-7802568-B2 | Cartridge for a liquid | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-28 | — | — | US | disclosed |
| US-20060016449-A1 | Cartridge for a liquid | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-01-26 | — | — | US | disclosed |
| US-6988496-B1 | Cartridge for a liquid | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-01-24 | — | — | US | disclosed |
| EP-1426373-A1 | Method for producing the anticholinergic agent tiotropium bromide | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2004-06-09 | — | — | EP | disclosed |
| US-6223933-B1 | Pressure compensation device for a two-part container | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2001-05-01 | — | — | US | disclosed |