Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.70 |
| ▸ | CASP3 | P42574 | 2/20 | 0.70 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.70 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.70 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.50 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.50 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.50 |
| ▸ | NSD2 | O96028 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11749167 | 0.84 | NPC1 (1.00) | NPC1CASP3SENP8SENP7SENP6 | |
| SCHEMBL11123647 | 0.82 | ALDH1A1 (0.67) | NPC1ALDH1A1KMT2AMAPTRAB9A | |
| SCHEMBL22198249 | 0.82 | SMN1; SMN2 (0.71) | NPC1ALDH1A1KMT2AMAPTRAB9A | |
| SCHEMBL22198159 | 0.82 | ALDH1A1 (0.67) | NPC1ALDH1A1KMT2AMAPTRAB9A | |
| SCHEMBL22198263 | 0.82 | ALDH1A1 (0.59) | NPC1CASP3SENP8SENP7SENP6 | |
| SCHEMBL22198251 | 0.82 | NPC1 (0.68) | NPC1CASP3SENP8SENP7SENP6 | |
| SCHEMBL22198305 | 0.82 | CHRM5 (0.68) | NPC1CASP3SENP8SENP7SENP6 | |
| SCHEMBL22198258 | 0.82 | APP (0.69) | NPC1CASP3SENP8SENP7SENP6 | |
| SCHEMBL22198126 | 0.82 | GRIN2D (0.68) | NPC1ALDH1A1KMT2AMAPTRAB9A | |
| SCHEMBL10909091 | 0.82 | GRIN2D (0.68) | NPC1ALDH1A1KMT2AMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020140924-A1 | DIHYDRAZONE COMPOUNDS HAVING HIGH AFFINITY TO AΒ PROTEIN AND TAU PROTEIN, DERIVATIVES THEREOF AND USE THEREOF | 原子高科股份有限公司 | 2020-07-09 | — | — | WO | disclosed |