Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.67 |
| ▸ | MAPT | P10636 | 5/20 | 0.67 |
| ▸ | NPC1 | O15118 | 5/20 | 0.67 |
| ▸ | RAB9A | P51151 | 5/20 | 0.67 |
| ▸ | MEN1 | O00255 | 5/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | RELA | Q04206 | 1/20 | 0.67 |
| ▸ | GLA | P06280 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.59 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.59 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.59 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.59 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.59 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.59 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.59 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22198159 | 1.00 | ALDH1A1 (0.67) | ALDH1A1KMT2ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL22198126 | 0.91 | GRIN2D (0.68) | ALDH1A1KMT2ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL10909091 | 0.91 | GRIN2D (0.68) | ALDH1A1KMT2ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL22198165 | 0.90 | ALDH1A1 (0.61) | ALDH1A1KMT2ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL22198164 | 0.86 | ALDH1A1 (0.56) | ALDH1A1KMT2ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL22198249 | 0.83 | SMN1; SMN2 (0.71) | ALDH1A1KMT2ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL22198259 | 0.82 | NPC1 (0.70) | ALDH1A1KMT2ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL22198277 | 0.82 | APP (0.68) | ALDH1A1KMT2ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL22198157 | 0.82 | ALDH1A1 (0.60) | ALDH1A1KMT2ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL22198158 | 0.82 | MAPT (0.58) | ALDH1A1KMT2ASMN1; SMN2MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0027917-B1 | REAGENT AND PROCESS FOR THE DETERMINATION OF HYDRAZINE | MERCK PATENT GmbH (DE) | 1984-10-10 | — | — | EP | disclosed |
| EP-0027917-A1 | Reagent and process for the determination of hydrazine | MERCK PATENT GmbH (DE) | 1981-05-06 | — | — | EP | disclosed |