Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 13/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 3/20 | 0.40 |
| ▸ | ATAD2 | Q6PL18 | 11/20 | 0.39 |
| ▸ | DDO | Q99489 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22185211 | 0.81 | TNF (0.41) | TNFRIPK1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL3363264 | 0.80 | DAO (0.61) | TNFRIPK1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL22184937 | 0.80 | EIF4A3 (0.40) | TNFRIPK1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL22198970 | 0.78 | HRH4 (0.45) | BRD4GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL22198968 | 0.78 | NQO2 (0.43) | BRD4GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL12970395 | 0.76 | DAO (0.65) | BRD4DAOATAD2DDO | |
| SCHEMBL25310064 | 0.73 | BRD4 (0.42) | BRD4DAOATAD2DDO | |
| SCHEMBL30482258 | 0.73 | BRD4 (0.42) | BRD4DAOATAD2DDO | |
| SCHEMBL25262124 | 0.73 | PARP1 (0.44) | BRD4DAOATAD2DDO | |
| SCHEMBL30482246 | 0.73 | PARP1 (0.44) | BRD4DAOATAD2DDO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020141439-A1 | HETEROCYCLIC COMPOUNDS AS MUTANT IDH INHIBITORS | INTEGRAL BIOSCIENCES PRIVATE LIMITED (IN) | 2020-07-09 | — | — | WO | disclosed |