Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 16/20 | 0.61 |
| ▸ | DDO | Q99489 | 7/20 | 0.61 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.41 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3364081 | 0.83 | DAO (0.65) | DAODDOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL22198962 | 0.80 | TNF (0.43) | DAODDOTNFRIPK1GRIN2D | |
| SCHEMBL3435254 | 0.80 | DAO (0.61) | DAODDO | |
| SCHEMBL3363037 | 0.80 | DAO (0.61) | DAODDO | |
| SCHEMBL3361624 | 0.78 | DAO (0.58) | DAODDO | |
| SCHEMBL3432869 | 0.78 | DAO (0.58) | DAODDO | |
| SCHEMBL22185211 | 0.78 | TNF (0.41) | DAODDOTNFRIPK1GRIN2D | |
| SCHEMBL22184937 | 0.76 | EIF4A3 (0.40) | DAODDOTNFRIPK1GRIN2D | |
| SCHEMBL3424009 | 0.76 | DAO (0.57) | DAODDO | |
| SCHEMBL3362300 | 0.76 | DAO (1.00) | DAODDO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010058314-A1 | HYDROXYQUINOLIN-2(1H)-ONES AND DERIVATIVES THEREOF | PFIZER INC. (US) | 2010-05-27 | — | — | WO | claimed |
| WO-2010058314-A1 | HYDROXYQUINOLIN-2(1H)-ONES AND DERIVATIVES THEREOF | PFIZER INC. (US) | 2010-05-27 | — | — | WO | disclosed |