Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS8 | O00214 | 1/20 | 0.45 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.45 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.33 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.33 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.33 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.33 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.33 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.33 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.33 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.33 |
| ▸ | PYGB | P11216 | 3/20 | 0.33 |
| ▸ | SELP | P16109 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19774686 | 1.00 | LGALS8 (0.45) | LGALS8LGALS3LGALS4MAPK1SLC5A1 | |
| SCHEMBL23025973 | 1.00 | LGALS8 (0.45) | LGALS8LGALS3LGALS4MAPK1SLC5A1 | |
| SCHEMBL20306671 | 0.90 | LGALS8 (0.49) | LGALS8LGALS3LGALS4MAPK1 | |
| SCHEMBL16148734 | 0.89 | LGALS8 (0.51) | LGALS8LGALS3LGALS4MAPK1 | |
| SCHEMBL16148735 | 0.89 | LGALS8 (0.51) | LGALS8LGALS3LGALS4MAPK1 | |
| SCHEMBL19297763 | 0.88 | LGALS8 (0.35) | LGALS8LGALS3LGALS4 | |
| SCHEMBL19772749 | 0.88 | LGALS8 (0.53) | LGALS8LGALS3LGALS4MAPK1 | |
| SCHEMBL24155775 | 0.88 | LGALS8 (0.53) | LGALS8LGALS3LGALS4MAPK1 | |
| SCHEMBL469613 | 0.88 | LGALS8 (0.53) | LGALS8LGALS3LGALS4MAPK1 | |
| SCHEMBL24473712 | 0.86 | LGALS3 (0.41) | LGALS8LGALS3LGALS4MAPK1SLC5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3677679-A1 | SIRNA MOLECULE INHIBITING PCSK9 GENE EXPRESSION AND APPLICATION THEREOF | Guangzhou Ribobio Co., Ltd. (CN) | 2020-07-08 | — | — | EP | disclosed |