Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29356303 | 0.85 | BRAF (0.36) | AKT1AKT2 | |
| SCHEMBL22191516 | 0.85 | BRAF (0.36) | AKT1AKT2 | |
| SCHEMBL22191217 | 0.78 | AKT1 (0.33) | AKT1AKT2 | |
| SCHEMBL29358839 | 0.78 | AKT1 (0.33) | AKT1AKT2 | |
| SCHEMBL22200682 | 0.73 | FGFR1 (0.44) | — | |
| SCHEMBL25035601 | 0.73 | F2 (0.37) | — | |
| SCHEMBL22200335 | 0.72 | WEE1 (0.34) | — | |
| SCHEMBL29352947 | 0.72 | BRAF (0.36) | — | |
| SCHEMBL22191327 | 0.72 | BRAF (0.36) | — | |
| SCHEMBL22191477 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142612-A1 | PYRIDO-PYRIMIDINONE AND PTERIDINONE COMPOUNDS AS INHIBITORS OF ENDORIBONUCLEASE INOSITOL REQUIRING ENZYME I (IRE I ALPHA) FOR THE TREATMENT OF CANCER DISEASES. | GENENTECH, INC. (US) | 2020-07-09 | — | — | WO | disclosed |