Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22200697 | 0.77 | BRAF (0.40) | FGFR1BRAF | |
| SCHEMBL22200335 | 0.76 | WEE1 (0.34) | FGFR1BRAF | |
| SCHEMBL22200682 | 0.72 | FGFR1 (0.44) | FGFR1BRAF | |
| SCHEMBL29353158 | 0.72 | ERN1 (0.39) | BRAF | |
| SCHEMBL22191003 | 0.72 | ERN1 (0.39) | BRAF | |
| SCHEMBL25035677 | 0.72 | BRAF (0.47) | BRAF | |
| SCHEMBL29354977 | 0.71 | ERN1 (0.39) | BRAF | |
| SCHEMBL22190942 | 0.71 | ERN1 (0.39) | BRAF | |
| SCHEMBL22200536 | 0.69 | BRAF (0.38) | FGFR1BRAF | |
| SCHEMBL22200519 | 0.68 | ERN1 (0.42) | FGFR1BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142612-A1 | PYRIDO-PYRIMIDINONE AND PTERIDINONE COMPOUNDS AS INHIBITORS OF ENDORIBONUCLEASE INOSITOL REQUIRING ENZYME I (IRE I ALPHA) FOR THE TREATMENT OF CANCER DISEASES. | GENENTECH, INC. (US) | 2020-07-09 | — | — | WO | disclosed |