Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | TLR4 | O00206 | 1/20 | 0.33 |
| ▸ | TLR2 | O60603 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6289223 | 0.91 | TP53 (0.40) | TP53TDP1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL4592330 | 0.88 | TP53 (0.38) | TP53TDP1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL27603153 | 0.87 | TP53 (0.37) | TP53TDP1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL5016969 | 0.83 | TP53 (0.42) | TP53TDP1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL5017313 | 0.81 | TP53 (0.40) | TP53TDP1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL411572 | 0.80 | TP53 (0.48) | TP53TDP1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL409170 | 0.80 | TP53 (0.42) | TP53TDP1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL7776977 | 0.80 | TP53 (0.42) | TP53TDP1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL1360257 | 0.80 | TP53 (0.39) | TP53TDP1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL2413304 | 0.79 | KDM4E (0.38) | TP53TDP1ALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200218154-A1 | RESIST COMPOSITION AND PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2020-07-09 | — | — | US | disclosed |