Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | TLR4 | O00206 | 1/20 | 0.32 |
| ▸ | TLR2 | O60603 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201015 | 0.88 | TP53 (0.44) | TP53TDP1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL27603153 | 0.84 | TP53 (0.37) | TP53TDP1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL27524551 | 0.84 | MCHR1 (0.39) | TP53TDP1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL6289223 | 0.82 | TP53 (0.40) | TP53TDP1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL16536303 | 0.77 | TP53 (0.35) | TP53TDP1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL5017313 | 0.77 | TP53 (0.40) | TP53TDP1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL409170 | 0.76 | TP53 (0.42) | TP53TDP1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL7776977 | 0.76 | TP53 (0.42) | TP53TDP1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL5016969 | 0.76 | TP53 (0.42) | TP53TDP1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL2413304 | 0.75 | KDM4E (0.38) | TP53TDP1ALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902019-A1 | SULPHONIUM SALT INITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) | 2008-03-26 | — | — | EP | disclosed |
| EP-1769286-A2 | OXIME DERIVATIVES AND THE USE THEROF AS LATENT ACIDS | Ciba Specialty Chemicals Holding Inc. (CH) | 2007-04-04 | — | — | EP | disclosed |
| WO-2007003507-A1 | SULPHONIUM SALT INITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2007-01-11 | — | — | WO | disclosed |
| WO-2006008250-A2 | OXIME DERIVATIVES AND THE USE THEROF AS LATENT ACIDS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2006-01-26 | — | — | WO | disclosed |