Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 6/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 5/20 | 0.41 |
| ▸ | EP300 | Q09472 | 2/20 | 0.41 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.41 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22190336 | 0.78 | HDAC8 (0.41) | HDAC8DDB1CRBNEP300CTSD | |
| SCHEMBL22559986 | 0.77 | CTSD (0.44) | CREBBPBRD4CTSD | |
| SCHEMBL6976103 | 0.76 | CTSD (0.49) | CREBBPDDB1CRBNCTSD | |
| SCHEMBL6968377 | 0.76 | CTSD (0.49) | CREBBPDDB1CRBNCTSD | |
| SCHEMBL6976101 | 0.76 | CTSD (0.49) | CREBBPDDB1CRBNCTSD | |
| SCHEMBL7385153 | 0.76 | HDAC8 (0.47) | CREBBPHDAC8DDB1CRBNBRD4 | |
| SCHEMBL7385157 | 0.76 | HDAC8 (0.47) | CREBBPHDAC8DDB1CRBNBRD4 | |
| SCHEMBL5136681 | 0.71 | EP300 (0.44) | HDAC8DDB1CRBNEP300GBA1 | |
| SCHEMBL16889105 | 0.71 | — | — | |
| SCHEMBL5136682 | 0.71 | EP300 (0.44) | HDAC8DDB1CRBNEP300GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020141734-A1 | METHOD FOR PREPARING CHIRAL GAMMA-LACTAM COMPOUND AND METAL COMPLEX THEREFOR | 기초과학연구원 | 2020-07-09 | — | — | WO | disclosed |