Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 19/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201414 | 0.87 | ABCG2 (0.50) | ABCG2 | |
| SCHEMBL22201411 | 0.87 | ABCG2 (0.50) | ABCG2 | |
| SCHEMBL22201604 | 0.86 | ALDH1A1 (0.66) | ABCG2KDM4EALDH1A1RXFP1 | |
| SCHEMBL22201409 | 0.85 | ABCG2 (0.48) | ABCG2 | |
| SCHEMBL22201462 | 0.85 | ABCG2 (0.48) | ABCG2KDM4EALDH1A1RXFP1 | |
| SCHEMBL22201406 | 0.85 | ABCG2 (0.55) | ABCG2 | |
| SCHEMBL22201695 | 0.84 | ALDH1A1 (0.49) | ABCG2KDM4EALDH1A1RXFP1 | |
| SCHEMBL22201410 | 0.84 | ABCG2 (0.47) | ABCG2 | |
| SCHEMBL22201420 | 0.82 | LATS1 (0.54) | ABCG2KDM4EALDH1A1RXFP1 | |
| SCHEMBL22201422 | 0.82 | ABCG2 (0.60) | ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |