Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.66 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | PDE5A | O76074 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | ABCG2 | Q9UNQ0 | 12/20 | 0.62 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.62 |
| ▸ | GSK3A | P49840 | 1/20 | 0.60 |
| ▸ | GSK3B | P49841 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.59 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.59 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201601 | 0.91 | ALDH1A1 (0.66) | ALDH1A1KDM4ERXFP1HPGDPOLB | |
| SCHEMBL22201420 | 0.89 | LATS1 (0.54) | ALDH1A1KDM4ERXFP1HPGDPOLB | |
| SCHEMBL22201695 | 0.87 | ALDH1A1 (0.49) | ALDH1A1KDM4ERXFP1HPGDPOLB | |
| SCHEMBL22201615 | 0.86 | ALDH1A1 (0.59) | ALDH1A1KDM4ERXFP1HPGDPOLB | |
| SCHEMBL22201457 | 0.86 | ALDH1A1 (0.59) | ALDH1A1KDM4ERXFP1HPGDPOLB | |
| SCHEMBL22201413 | 0.86 | ABCG2 (0.53) | ALDH1A1KDM4ERXFP1ABCG2 | |
| SCHEMBL22201464 | 0.84 | POLB (0.58) | ALDH1A1KDM4ERXFP1HPGDPOLB | |
| SCHEMBL22201461 | 0.84 | ABCG2 (0.66) | ALDH1A1KDM4ERXFP1HPGDPOLB | |
| SCHEMBL22201428 | 0.82 | ALDH1A1 (0.81) | ALDH1A1KDM4ERXFP1HPGDPOLB | |
| SCHEMBL22201460 | 0.81 | PRKD1 (0.68) | ALDH1A1KDM4ERXFP1HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |