Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 12/20 | 0.66 |
| ▸ | HPGD | P15428 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | PDE5A | O76074 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | GSK3A | P49840 | 1/20 | 0.58 |
| ▸ | GSK3B | P49841 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CASP1 | P29466 | 1/20 | 0.57 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.57 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201471 | 0.85 | KDM4E (0.66) | ABCG2HPGDALDH1A1KDM4EPOLB | |
| SCHEMBL22201556 | 0.82 | HPGD (0.62) | ABCG2HPGDALDH1A1KDM4EPOLB | |
| SCHEMBL22201557 | 0.82 | ALDH1A1 (0.59) | ABCG2HPGDALDH1A1KDM4EPOLB | |
| SCHEMBL22201558 | 0.82 | ALDH1A1 (0.59) | ABCG2HPGDALDH1A1KDM4EPOLB | |
| SCHEMBL22201555 | 0.82 | ALDH1A1 (0.59) | ABCG2HPGDALDH1A1KDM4EPOLB | |
| SCHEMBL22201559 | 0.82 | HPGD (0.58) | ABCG2HPGDALDH1A1KDM4EPOLB | |
| SCHEMBL22201571 | 0.79 | ABCG2 (1.00) | ABCG2HPGDALDH1A1KDM4EPOLB | |
| SCHEMBL22201568 | 0.78 | HPGD (0.71) | ABCG2HPGDALDH1A1KDM4EPOLB | |
| SCHEMBL22201672 | 0.78 | HPGD (0.64) | ABCG2HPGDALDH1A1KDM4EPOLB | |
| SCHEMBL3460305 | 0.77 | ALDH1A1 (0.94) | ABCG2HPGDALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |