Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 14/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 8/20 | 0.52 |
| ▸ | ABCC1 | P33527 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201611 | 0.87 | LMNA (0.49) | ABCG2ABCB1ABCC1MEN1KMT2A | |
| SCHEMBL22201459 | 0.86 | ABCG2 (0.51) | ABCG2ABCB1ABCC1MEN1KMT2A | |
| SCHEMBL22201558 | 0.84 | ALDH1A1 (0.59) | ABCG2ABCB1ABCC1MEN1KMT2A | |
| SCHEMBL22201687 | 0.82 | ABCG2 (0.54) | ABCG2ABCB1ABCC1MEN1KMT2A | |
| SCHEMBL22201297 | 0.81 | ABCG2 (0.50) | ABCG2 | |
| SCHEMBL22201689 | 0.81 | ABCG2 (0.48) | ABCG2ABCB1ABCC1MEN1KMT2A | |
| SCHEMBL22201465 | 0.81 | HPGD (0.50) | ABCG2ABCB1ABCC1MEN1KMT2A | |
| SCHEMBL22201359 | 0.80 | LATS1 (0.48) | ABCG2ABCB1ABCC1MEN1KMT2A | |
| SCHEMBL22201688 | 0.79 | KDM4E (0.53) | ABCG2ABCB1ABCC1MEN1KMT2A | |
| SCHEMBL22201694 | 0.76 | KDM4E (0.56) | ABCG2ABCB1ABCC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |