Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 11/20 | 0.65 |
| ▸ | ACP1 | P24666 | 3/20 | 0.64 |
| ▸ | PDE5A | O76074 | 3/20 | 0.62 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | LATS1 | O95835 | 2/20 | 0.59 |
| ▸ | LATS2 | Q9NRM7 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3460201 | 0.85 | ACP1 (0.84) | GBA1ACP1PDE5AKMT2ALATS1 | |
| SCHEMBL1083972 | 0.84 | ACP1 (0.85) | GBA1ACP1PDE5AKMT2ALATS1 | |
| SCHEMBL22201548 | 0.82 | ACP1 (0.73) | GBA1ACP1PDE5AKMT2ALATS1 | |
| SCHEMBL3459522 | 0.82 | CYP1A2 (0.71) | GBA1ACP1PDE5ALMNAMAPT | |
| SCHEMBL4867358 | 0.79 | ACP1 (1.00) | GBA1ACP1PDE5ALMNAMAPT | |
| SCHEMBL15977158 | 0.78 | SMN1; SMN2 (0.60) | GBA1ACP1PDE5ALMNAMAPT | |
| SCHEMBL3459788 | 0.78 | GBA1 (0.57) | GBA1ACP1PDE5ALMNAMAPT | |
| SCHEMBL1083845 | 0.77 | ACP1 (1.00) | GBA1ACP1PDE5ATLR7LMNA | |
| SCHEMBL3459470 | 0.77 | GBA1 (0.84) | GBA1ACP1PDE5ALATS1LATS2 | |
| SCHEMBL3459452 | 0.77 | GBA1 (0.84) | GBA1ACP1PDE5ALATS1LATS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |