SCHEMBL4867358

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1083845	0.94	ACP1 (1.00)	ACP1PDE5AGBA1CYP1A2CYP3A4
	SCHEMBL4862541	0.92	ACP1 (1.00)	ACP1PDE5AGBA1CYP1A2CYP3A4
	SCHEMBL18353959	0.87	GBA1 (1.00)	ACP1GBA1LMNAMAPT
	SCHEMBL18354432	0.86	GBA1 (1.00)	ACP1PDE5AGBA1
	SCHEMBL3460201	0.86	ACP1 (0.84)	ACP1PDE5AGBA1CYP1A2CYP3A4
	SCHEMBL22201548	0.85	ACP1 (0.73)	ACP1PDE5AGBA1CYP1A2CYP3A4
	SCHEMBL1083972	0.84	ACP1 (0.85)	ACP1PDE5AGBA1CYP1A2CYP3A4
	SCHEMBL3459522	0.82	CYP1A2 (0.71)	ACP1PDE5AGBA1CYP1A2CYP3A4
	SCHEMBL18353962	0.82	GBA1 (1.00)	ACP1PDE5AGBA1
	SCHEMBL18354085	0.82	GBA1 (1.00)	ACP1PDE5AGBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.