Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 3/20 | 0.73 |
| ▸ | GBA1 | P04062 | 12/20 | 0.70 |
| ▸ | LATS1 | O95835 | 2/20 | 0.67 |
| ▸ | LATS2 | Q9NRM7 | 2/20 | 0.67 |
| ▸ | PDE5A | O76074 | 3/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3460201 | 0.88 | ACP1 (0.84) | ACP1GBA1LATS1LATS2PDE5A | |
| SCHEMBL1083972 | 0.87 | ACP1 (0.85) | ACP1GBA1LATS1LATS2PDE5A | |
| SCHEMBL4867358 | 0.85 | ACP1 (1.00) | ACP1GBA1PDE5ACYP1A2CYP3A4 | |
| SCHEMBL3459522 | 0.85 | CYP1A2 (0.71) | ACP1GBA1LATS1LATS2PDE5A | |
| SCHEMBL22201472 | 0.82 | GBA1 (0.65) | ACP1GBA1LATS1LATS2PDE5A | |
| SCHEMBL26177092 | 0.80 | LATS1 (1.00) | ACP1GBA1LATS1LATS2 | |
| SCHEMBL1083845 | 0.80 | ACP1 (1.00) | ACP1GBA1LATS1LATS2PDE5A | |
| SCHEMBL3459452 | 0.80 | GBA1 (0.84) | ACP1GBA1LATS1LATS2PDE5A | |
| SCHEMBL3459470 | 0.80 | GBA1 (0.84) | ACP1GBA1LATS1LATS2PDE5A | |
| SCHEMBL18353959 | 0.80 | GBA1 (1.00) | ACP1GBA1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |