Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 10/20 | 0.64 |
| ▸ | MEN1 | O00255 | 7/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.61 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.60 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.58 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.58 |
| ▸ | PDE5A | O76074 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5107131 | 0.86 | MEN1 (0.73) | ABCG2MEN1KMT2ANTSR1POLB | |
| SCHEMBL2291715 | 0.78 | MEN1 (0.67) | ABCG2MEN1KMT2ANTSR1POLB | |
| SCHEMBL2233756 | 0.75 | MAPT (0.62) | ABCG2MEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL28797852 | 0.75 | NPSR1 (0.65) | ABCG2MEN1KMT2ANTSR1POLB | |
| SCHEMBL13945469 | 0.75 | MEN1 (1.00) | ABCG2MEN1KMT2ANTSR1POLB | |
| SCHEMBL1084181 | 0.74 | KMT2A (0.72) | ABCG2MEN1KMT2APOLBCYP1A2 | |
| SCHEMBL13585538 | 0.74 | KMT2A (0.56) | ABCG2MEN1KMT2APOLBCYP1A2 | |
| SCHEMBL4891835 | 0.74 | ABCG2 (0.69) | ABCG2MEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL12176115 | 0.73 | MEN1 (1.00) | ABCG2MEN1KMT2ANTSR1POLB | |
| SCHEMBL22201363 | 0.73 | POLB (0.71) | ABCG2MEN1KMT2ANTSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |