Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 13/20 | 0.83 |
| ▸ | POLB | P06746 | 2/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.76 |
| ▸ | LMNA | P02545 | 1/20 | 0.76 |
| ▸ | HPGD | P15428 | 1/20 | 0.76 |
| ▸ | GSK3A | P49840 | 1/20 | 0.76 |
| ▸ | GSK3B | P49841 | 1/20 | 0.76 |
| ▸ | MEN1 | O00255 | 7/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.73 |
| ▸ | TP53 | P04637 | 2/20 | 0.73 |
| ▸ | MAPT | P10636 | 2/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.73 |
| ▸ | GAA | P10253 | 3/20 | 0.70 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.69 |
| ▸ | GBA1 | P04062 | 1/20 | 0.66 |
| ▸ | KDM1A | O60341 | 1/20 | 0.62 |
| ▸ | PDE5A | O76074 | 1/20 | 0.62 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1083761 | 0.86 | HPGD (1.00) | ABCG2POLBALDH1A1LMNAHPGD | |
| SCHEMBL1058652 | 0.84 | ABCG2 (1.00) | ABCG2MEN1KMT2ATP53MAPT | |
| SCHEMBL1061916 | 0.83 | ABCG2 (1.00) | ABCG2POLBALDH1A1LMNAMEN1 | |
| SCHEMBL22201289 | 0.82 | ABCG2 (0.79) | ABCG2POLBALDH1A1LMNAHPGD | |
| SCHEMBL1083806 | 0.82 | MEN1 (0.71) | ABCG2POLBALDH1A1LMNAHPGD | |
| SCHEMBL12316824 | 0.80 | GAA (1.00) | ABCG2POLBLMNAMEN1KMT2A | |
| SCHEMBL6001888 | 0.78 | ABCG2 (0.72) | ABCG2POLBALDH1A1LMNAHPGD | |
| SCHEMBL22201553 | 0.78 | KDM1A (0.66) | ABCG2POLBMEN1KMT2ATP53 | |
| SCHEMBL1063103 | 0.78 | ABCG2 (1.00) | ABCG2POLBALDH1A1LMNAHPGD | |
| SCHEMBL22201264 | 0.77 | ABCG2 (0.71) | ABCG2POLBALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |