Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 14/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.76 |
| ▸ | LMNA | P02545 | 2/20 | 0.76 |
| ▸ | HPGD | P15428 | 2/20 | 0.76 |
| ▸ | POLB | P06746 | 1/20 | 0.76 |
| ▸ | GSK3A | P49840 | 1/20 | 0.76 |
| ▸ | GSK3B | P49841 | 1/20 | 0.76 |
| ▸ | KDM1A | O60341 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | EGFR | P00533 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1083761 | 0.86 | HPGD (1.00) | ABCG2ALDH1A1LMNAHPGDPOLB | |
| SCHEMBL14474617 | 0.83 | ABCG2 (0.80) | ABCG2ALDH1A1LMNAHPGDPOLB | |
| SCHEMBL14475538 | 0.83 | ABCG2 (0.60) | ABCG2ALDH1A1LMNAHPGDPOLB | |
| SCHEMBL14474568 | 0.83 | ABCG2 (0.60) | ABCG2ALDH1A1LMNAHPGDPOLB | |
| SCHEMBL22201628 | 0.82 | ABCG2 (0.83) | ABCG2ALDH1A1LMNAHPGDPOLB | |
| SCHEMBL1083806 | 0.80 | MEN1 (0.71) | ABCG2ALDH1A1LMNAHPGDPOLB | |
| SCHEMBL22201264 | 0.80 | ABCG2 (0.71) | ABCG2ALDH1A1LMNAHPGDPOLB | |
| SCHEMBL22201484 | 0.80 | HPGD (0.71) | ABCG2ALDH1A1LMNAHPGDPOLB | |
| SCHEMBL1064930 | 0.79 | TGFBR1 (0.78) | ABCG2ALDH1A1LMNAHPGDPOLB | |
| SCHEMBL14475062 | 0.78 | KDM1A (0.57) | ABCG2ALDH1A1LMNAHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |