Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6544638 | 0.88 | EPHX2 (0.31) | EPHX2 | |
| SCHEMBL6384635 | 0.79 | EPHX2 (0.36) | EPHX2 | |
| SCHEMBL2220877 | 0.73 | — | — | |
| SCHEMBL12463565 | 0.73 | — | — | |
| SCHEMBL15177067 | 0.67 | — | — | |
| SCHEMBL13559593 | 0.64 | — | — | |
| SCHEMBL13222126 | 0.60 | — | — | |
| SCHEMBL10620118 | 0.56 | ALDH1A1 (0.41) | — | |
| SCHEMBL6864335 | 0.56 | — | — | |
| SCHEMBL25187984 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115433194-B | Synthesis method of hexahydro-3 aH-furan [2,3-c ] pyrrole-3 a-carboxylic acid methyl ester derivative | 上海毕得医药科技股份有限公司 | 2023-06-23 | — | — | CN | claimed |
| CN-115433194-A | Synthetic method of hexahydro-3 aH-furan [2,3-c ] pyrrole-3 a-carboxylic acid methyl ester derivative | 上海毕得医药科技股份有限公司 | 2022-12-06 | — | — | CN | claimed |
| CN-115433194-B | Synthesis method of hexahydro-3 aH-furan [2,3-c ] pyrrole-3 a-carboxylic acid methyl ester derivative | 上海毕得医药科技股份有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-115433194-B | Synthesis method of hexahydro-3 aH-furan [2,3-c ] pyrrole-3 a-carboxylic acid methyl ester derivative | 上海毕得医药科技股份有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-115433194-A | Synthetic method of hexahydro-3 aH-furan [2,3-c ] pyrrole-3 a-carboxylic acid methyl ester derivative | 上海毕得医药科技股份有限公司 | 2022-12-06 | — | — | CN | disclosed |
| CN-115433194-A | Synthetic method of hexahydro-3 aH-furan [2,3-c ] pyrrole-3 a-carboxylic acid methyl ester derivative | 上海毕得医药科技股份有限公司 | 2022-12-06 | — | — | CN | disclosed |
| CN-107417648-B | Synthetic method of 3-aminomethyl tetrahydrofuran | 中国科学院兰州化学物理研究所 | 2020-05-19 | — | — | CN | disclosed |
| EP-2515657-A1 | TYROSINE KINASE INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2012-10-31 | — | — | EP | disclosed |
| US-20120264735-A1 | TYROSINE KINASE INHIBITORS | MERCK SHARP & DOHME CORP. | 2012-10-18 | — | — | US | disclosed |
| US-20120264735-A1 | TYROSINE KINASE INHIBITORS | MERCK SHARP & DOHME CORP. | 2012-10-18 | — | — | US | disclosed |
| WO-2011084402-A1 | TYROSINE KINASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2011-07-14 | — | — | WO | disclosed |
| EP-1250330-B1 | PROCESS FOR THE PREPARATION OF 3-FUROATE ESTERS AND NOVEL INTERMEDIATE COMPOUNDS | EASTMAN CHEM CO (US) | 2004-01-07 | — | — | EP | disclosed |
| EP-1250330-A1 | PROCESS FOR THE PREPARATION OF 3-FUROATE ESTERS AND NOVEL INTERMEDIATE COMPOUNDS | EASTMAN CHEMICAL COMPANY (US) | 2002-10-23 | — | — | EP | disclosed |
| WO-2001055127-A1 | PROCESS FOR THE PREPARATION OF 3-FUROATE ESTERS AND NOVEL INTERMEDIATE COMPOUNDS | EASTMAN CHEMICAL COMPANY (US) | 2001-08-02 | — | — | WO | disclosed |
| US-6184394-B1 | ALKYL 3-FUROATES FROM 4-ACYL-2,3-DIHYDROFURANS FROM 4-ACYL-2,3-DIHYDRO-FURANS BY HALOGENATING IN THE PRESENCE OF AN ALKANOL FOLLOWED BY CONTACTING WITH A STRONG BASE; DRUGS; ANTINFLAMMATORY AND -FOULING AGENTS | EASTMAN CHEMICAL COMPANY | 2001-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120264735-A1 | TYROSINE KINASE INHIBITORS | ABL1, MET, ERBB2 | EPHX2 3003/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.