Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD1 | Q15139 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 6/20 | 0.47 |
| ▸ | FLT1 | P17948 | 5/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 7/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.45 |
| ▸ | FLT3 | P36888 | 1/20 | 0.45 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.44 |
| ▸ | ULK1 | O75385 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201330 | 0.82 | TGFBR1 (0.62) | PRKD1EGFRFLT1KDRTGFBR1 | |
| SCHEMBL22201394 | 0.81 | FGFR2 (0.54) | PRKD1EGFRFLT1GRM4CYP1A2 | |
| SCHEMBL14891306 | 0.77 | EGFR (0.48) | EGFRGRM4 | |
| SCHEMBL22803760 | 0.77 | GRM4 (0.50) | PRKD1EGFRFLT1GRM4CYP1A2 | |
| SCHEMBL30302489 | 0.77 | GRM4 (0.50) | PRKD1EGFRFLT1GRM4CYP1A2 | |
| SCHEMBL20568776 | 0.77 | GRM4 (0.51) | PRKD1GRM4CYP1A2TGFBR1 | |
| SCHEMBL22803759 | 0.76 | EGFR (0.52) | PRKD1EGFRFLT1GRM4CYP1A2 | |
| SCHEMBL30302562 | 0.76 | EGFR (0.52) | PRKD1EGFRFLT1GRM4CYP1A2 | |
| SCHEMBL22803770 | 0.75 | EGFR (0.58) | PRKD1EGFRFLT1GRM4CYP1A2 | |
| SCHEMBL30302532 | 0.75 | EGFR (0.58) | PRKD1EGFRFLT1GRM4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |