Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR2 | P21802 | 1/20 | 0.54 |
| ▸ | FLT3 | P36888 | 1/20 | 0.54 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.52 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 4/20 | 0.47 |
| ▸ | FLT1 | P17948 | 4/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | PDE5A | O76074 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GSK3A | P49840 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201341 | 0.85 | PRKD1 (0.66) | PRKD1TGFBR1KDM1AHPGDLMNA | |
| SCHEMBL22201397 | 0.83 | ABCG2 (0.55) | FGFR2FLT3PRKD1ABCG2 | |
| SCHEMBL22201355 | 0.82 | LMNA (0.52) | FGFR2FLT3PRKD1TGFBR1KDM1A | |
| SCHEMBL22201661 | 0.81 | PRKD1 (0.47) | FGFR2FLT3PRKD1TGFBR1EGFR | |
| SCHEMBL22201395 | 0.81 | FGFR2 (0.55) | FGFR2FLT3PRKD1TGFBR1KDM1A | |
| SCHEMBL22201353 | 0.79 | ABCG2 (0.54) | FGFR2FLT3PRKD1TGFBR1KDM1A | |
| SCHEMBL22201354 | 0.79 | HPGD (0.55) | FGFR2FLT3PRKD1TGFBR1KDM1A | |
| SCHEMBL22201356 | 0.79 | HPGD (0.55) | FGFR2FLT3PRKD1TGFBR1KDM1A | |
| SCHEMBL22201348 | 0.78 | PRKD1 (0.60) | FGFR2FLT3PRKD1TGFBR1KDM1A | |
| SCHEMBL1062778 | 0.78 | TGFBR1 (0.71) | PRKD1TGFBR1KDM1ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |