Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | TP53 | P04637 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 4/20 | 0.41 |
| ▸ | ACACA | Q13085 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22191192 | 0.83 | ALDH1A1 (0.53) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL22201743 | 0.83 | ALDH1A1 (0.53) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL19828239 | 0.78 | ALDH1A1 (0.74) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL25937463 | 0.77 | ALDH1A1 (0.47) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL25937575 | 0.77 | ALDH1A1 (0.47) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL37802 | 0.77 | ALDH1A1 (1.00) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL31537002 | 0.77 | ALDH1A1 (1.00) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL12289601 | 0.77 | ALDH1A1 (1.00) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL31537008 | 0.77 | ALDH1A1 (1.00) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL13806572 | 0.77 | ALDH1A1 (1.00) | ALDH1A1TP53TSHRHIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142450-A1 | POLYMER COMPOSITIONS COMPRISING COMPOUNDS DERIVED FROM BIOLOGY | ZYMERGEN INC. (US) | 2020-07-09 | — | — | WO | disclosed |