Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22191192 | 1.00 | ALDH1A1 (0.53) | ALDH1A1PKMGAALMNATDP1 | |
| SCHEMBL25937575 | 0.93 | ALDH1A1 (0.47) | ALDH1A1PKMGAALMNATDP1 | |
| SCHEMBL25937463 | 0.93 | ALDH1A1 (0.47) | ALDH1A1PKMGAALMNATDP1 | |
| SCHEMBL25937503 | 0.90 | ALDH1A1 (0.44) | ALDH1A1PKMGAALMNATDP1 | |
| SCHEMBL25937789 | 0.90 | KMT2A (0.44) | ALDH1A1PKMGAALMNATDP1 | |
| SCHEMBL22201878 | 0.88 | HRH3 (0.58) | ALDH1A1PKMGAALMNATDP1 | |
| SCHEMBL25937488 | 0.87 | HRH3 (0.50) | ALDH1A1PKMGAALMNAKMT2A | |
| SCHEMBL25937809 | 0.83 | HRH3 (0.43) | ALDH1A1PKMGAALMNATDP1 | |
| SCHEMBL22201744 | 0.83 | ALDH1A1 (0.60) | ALDH1A1PKMGAALMNATDP1 | |
| SCHEMBL24163841 | 0.83 | HRH3 (0.39) | ALDH1A1PKMGAALMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242491-A1 | DIMERS FROM BIOREACHABLE MOLECULES AS COPOLYMERS | ZYMERGEN INC. (US) | 2023-08-03 | — | — | US | disclosed |
| US-20230242720-A1 | MODULUS MODIFIERS AND FILMS THEREOF | ZYMERGEN ACQUISITION SUB, INC. | 2023-08-03 | — | — | US | disclosed |
| WO-2022006145-A1 | MODULUS MODIFIERS AND FILMS THEREOF | ZYMERGEN INC. (US) | 2022-01-06 | — | — | WO | disclosed |
| WO-2022006023-A1 | DIMERS FROM BIOREACHABLE MOLECULES AS COPOLYMERS | ZYMERGEN INC. (US) | 2022-01-06 | — | — | WO | disclosed |
| WO-2020142450-A1 | POLYMER COMPOSITIONS COMPRISING COMPOUNDS DERIVED FROM BIOLOGY | ZYMERGEN INC. (US) | 2020-07-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242491-A1 | DIMERS FROM BIOREACHABLE MOLECULES AS COPOLYMERS | HDHD5, HAO2, ALAD | ALDH1A1 2236/4885PKM 1647/4885GAA 2564/4885 |
| US-20230242720-A1 | MODULUS MODIFIERS AND FILMS THEREOF | SHBG, PTMS, SERPINA6 | ALDH1A1 4761/4885PKM 1286/4885GAA 4830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.