Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | TSPO | P30536 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13889647 | 0.73 | NPC1 (0.60) | NPC1RAB9ATSPOSMN1; SMN2KMT2A | |
| SCHEMBL22201796 | 0.72 | ALDH1A1 (0.52) | KMT2AMAPK1L3MBTL1POLBMEN1 | |
| SCHEMBL4287111 | 0.72 | MAPK1 (0.59) | NPC1RAB9ATSPOSMN1; SMN2KMT2A | |
| SCHEMBL22201707 | 0.67 | USP30 (0.41) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1690816 | 0.65 | NPC1 (0.82) | NPC1RAB9ATSPOSMN1; SMN2KMT2A | |
| SCHEMBL544272 | 0.65 | NPC1 (0.75) | NPC1RAB9ATSPOSMN1; SMN2KMT2A | |
| SCHEMBL3163935 | 0.65 | NPC1 (0.75) | NPC1RAB9ATSPOSMN1; SMN2KMT2A | |
| SCHEMBL4073987 | 0.65 | NPC1 (0.64) | NPC1RAB9ASMN1; SMN2KMT2AMAPK1 | |
| SCHEMBL7128011 | 0.64 | MEN1 (0.37) | NPC1RAB9AKMT2AMAPK1L3MBTL1 | |
| SCHEMBL991685 | 0.64 | RAB9A (0.72) | NPC1RAB9ATSPOSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200216670-A1 | THERMOSETTING SILICON-CONTAINING COMPOUND, COMPOSITION FOR FORMING A SILICON-CONTAINING FILM, AND PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2020-07-09 | — | — | US | disclosed |