Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ELANE | P08246 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 3/20 | 0.34 |
| ▸ | MMP9 | P14780 | 2/20 | 0.34 |
| ▸ | MMP14 | P50281 | 2/20 | 0.34 |
| ▸ | MMP13 | P45452 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | MMP16 | P51512 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13064047 | 1.00 | HTT (0.39) | HTTSMN1; SMN2HSD11B1LMNANPC1 | |
| SCHEMBL16260250 | 0.96 | HTT (0.37) | HTTSMN1; SMN2HSD11B1LMNANPC1 | |
| SCHEMBL19322782 | 0.93 | HTT (0.40) | HTTSMN1; SMN2HSD11B1LMNANPC1 | |
| SCHEMBL9915249 | 0.92 | HTT (0.39) | HTTSMN1; SMN2HSD11B1LMNANPC1 | |
| SCHEMBL12961576 | 0.92 | HSD11B1 (0.42) | HTTSMN1; SMN2HSD11B1ELANEMAPT | |
| SCHEMBL14231427 | 0.91 | HTT (0.40) | HTTSMN1; SMN2HSD11B1LMNANPC1 | |
| SCHEMBL10033513 | 0.91 | ALDH1A1 (0.41) | HTTSMN1; SMN2HSD11B1LMNANPC1 | |
| SCHEMBL14364715 | 0.91 | HTT (0.40) | HTTSMN1; SMN2HSD11B1LMNANPC1 | |
| SCHEMBL24300674 | 0.90 | HTT (0.39) | HTTSMN1; SMN2HSD11B1LMNANPC1 | |
| SCHEMBL12463906 | 0.90 | NPC1 (0.49) | HTTSMN1; SMN2HSD11B1LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10953142-B2 | Biological component adhesion-suppressing material | TORAY INDUSTRIES, INC. (JP) | 2021-03-23 | — | — | US | disclosed |
| US-20200215239-A1 | BIOLOGICAL COMPONENT ADHESION-SUPPRESSING MATERIAL | TORAY INDUSTRIES, INC. (JP) | 2020-07-09 | — | — | US | disclosed |