Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 20/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17412045 | 0.90 | GLS (0.81) | GLS | |
| SCHEMBL21907452 | 0.84 | GLS (0.78) | GLS | |
| SCHEMBL17419714 | 0.84 | GLS (0.91) | GLS | |
| SCHEMBL29752915 | 0.84 | GLS (0.91) | GLS | |
| SCHEMBL17411425 | 0.82 | GLS (0.83) | GLS | |
| SCHEMBL17411944 | 0.82 | GLS (0.84) | GLS | |
| SCHEMBL22203669 | 0.81 | GLS (0.73) | GLS | |
| SCHEMBL17411710 | 0.81 | GLS (0.86) | GLS | |
| SCHEMBL17412071 | 0.81 | GLS (0.62) | GLS | |
| SCHEMBL22203514 | 0.80 | GLS (0.81) | GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3677579-A1 | HETEROCYCLIC GLS1 INHIBITORS | Board of Regents, The University of Texas System (US) | 2020-07-08 | — | — | EP | disclosed |