Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL220775 | 1.00 | CYP1A2 (0.58) | CYP1A2CYP2C19MAPTKMT2ACYP2D6 | |
| SCHEMBL59841 | 1.00 | CYP1A2 (0.58) | CYP1A2CYP2C19MAPTKMT2ACYP2D6 | |
| Methyl Alcohol SCHEMBL29003577 | 0.98 | CYP1A2 (0.56) | CYP1A2CYP2C19MAPTKMT2ACYP2D6 | |
| Hydrochloric Acid SCHEMBL6369027 | 0.98 | CYP1A2 (0.56) | CYP1A2CYP2C19MAPTKMT2ACYP2D6 | |
| Hydrochloric Acid SCHEMBL304449 | 0.98 | CYP1A2 (0.56) | CYP1A2CYP2C19MAPTKMT2ACYP2D6 | |
| Hydrochloric Acid SCHEMBL1455022 | 0.98 | CYP1A2 (0.56) | CYP1A2CYP2C19MAPTKMT2ACYP2D6 | |
| SCHEMBL30577995 | 0.90 | CYP1A2 (0.50) | CYP1A2CYP2C19MAPTKMT2ACYP2D6 | |
| SCHEMBL5565841 | 0.90 | CYP1A2 (0.54) | CYP1A2CYP2C19MAPTKMT2ACYP2D6 | |
| SCHEMBL7384716 | 0.87 | CYP2C9 (0.57) | CYP1A2CYP2C19MAPTKMT2ACYP2D6 | |
| SCHEMBL18209210 | 0.87 | CYP1A2 (0.47) | CYP1A2CYP2C19MAPTKMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 192 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6759551-B1 | COMPOUND IS DISSOLVED, IN THE FREE AMINO ACID FORM OR IN THE SALIFIED FORM, IN A PH REGION OF LESS THAN APPROXIMATELY 4.5 OR GREATER THAN APPROXIMATELY 9, THEN PH IS GRADUALLY BROUGHT, BY ADDITION OF A BASE OR OF AN ACID RESPECTIVELY, TO NEUTRAL | BAYER CROPSCIENCE S.A. (FR) | 2004-07-06 | — | — | US | claimed |
| US-6570021-B2 | For producing fungicidal 2-imidazolin-5-one compounds | RHONE-POULENC AGRO (FR) | 2003-05-27 | — | — | US | claimed |
| EP-1226111-A1 | CHIRAL (S- OR R-METHYLPHENYLGLYCINE) AMINO ACID CRYSTAL AND METHOD FOR PREPARING SAME | AVENTIS CROPSCIENCE S.A. (FR) | 2002-07-31 | — | — | EP | claimed |
| US-20020038034-A1 | Intermediates for the preparation of 2-imidazolin-5-ones | BUFORN ALBERT (FR) | 2002-03-28 | — | — | US | claimed |
| WO-2001032603-A1 | CHIRAL (S- OR R-METHYLPHENYLGLYCINE) AMINO ACID CRYSTAL AND METHOD FOR PREPARING SAME | AVENTIS CROPSCIENCE S.A (FR) | 2001-05-10 | — | — | WO | claimed |
| US-4714696-A | Novel derivatives of arginine vasopressin antagonists | MEDICAL COLLEGE OF OHIO (US) | 1987-12-22 | — | — | US | claimed |
| EP-0061356-A2 | Antagonists of the antidiuretic and/or vasopressor action of arginine vasopressin | Medical College of Ohio (US) | 1982-09-29 | — | — | EP | claimed |
| US-20250011333-A1 | PYRAZOLO-QUINAZOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES SRL (IT) | 2025-01-09 | — | — | US | disclosed |
| US-11814444-B2 | Cyclic polypeptides for PCSK9 inhibition | RA PHARMACEUTICALS, INC. (US) | 2023-11-14 | — | — | US | disclosed |
| US-20210300935-A1 | PYRAZOLO-QUINAZOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS KINASE INHIBITORS | Nerviano Medical Sciences, S.R.L. (IT) | 2021-09-30 | — | — | US | disclosed |
| US-20200123132-A1 | ANTIVIRAL COMPOUNDS | GILEAD PHARMASSET LLC | 2020-04-23 | — | — | US | disclosed |
| EP-2838900-B1 | COMPOUNDS AND METHODS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES INC (US) | 2019-08-21 | — | — | EP | disclosed |
| US-10344019-B2 | Antiviral compounds | GILEAD PHARMASSET LLC (US) | 2019-07-09 | — | — | US | disclosed |
| US-5352788-A | Angiotensin antagonist | ELF SANOFI (FR) | 1994-10-04 | — | — | US | disclosed |
| WO-1994001410-A1 | FUNGICIDAL 2-IMIDAZOLINE-5-ONE AND 2-IMIDAZOLINE-5-THIONE DERIVATIVES | RHONE POULENC AGROCHIMIE (FR) | 1994-01-20 | — | — | WO | disclosed |
| US-5270317-A | N-substituted heterocyclic derivatives, their preparation and the pharmaceutical compositions in which they are present | ELF SANOFI (FR) | 1993-12-14 | — | — | US | disclosed |
| US-5268375-A | Dinitrogen heterocyclic derivatives N-substituted by a biphenylmethyl group, and the pharmaceutical compositions in which they are present | ELF SANOFI (FR) | 1993-12-07 | — | — | US | disclosed |
| EP-0189326-A2 | Derivatives of arginine vasopressin antagonists | Medical College of Ohio (US) | 1986-07-30 | — | — | EP | disclosed |
| EP-0061356-B1 | ANTAGONISTS OF THE ANTIDIURETIC AND/OR VASOPRESSOR ACTION OF ARGININE VASOPRESSIN | Medical College of Ohio (US) | 1985-07-17 | — | — | EP | disclosed |
| EP-0061356-A2 | Antagonists of the antidiuretic and/or vasopressor action of arginine vasopressin | Medical College of Ohio (US) | 1982-09-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210300935-A1 | PYRAZOLO-QUINAZOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS KINASE INHIBITORS | MAP3K5, MAP3K9, MAP4K2 | CYP1A2 1198/4885CYP2C19 658/4885MAPT 2476/4885 |
| US-20020038034-A1 | Intermediates for the preparation of 2-imidazolin-5-ones | ERG28, CYP51A1, CYP3A5 | CYP1A2 32/4885CYP2C19 237/4885MAPT 3696/4885 |
| US-10344019-B2 | Antiviral compounds | MAVS, EIF2AK2, ZC3HAV1 | CYP1A2 3826/4885CYP2C19 3298/4885MAPT 2923/4885 |
| US-20250011333-A1 | PYRAZOLO-QUINAZOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS KINASE INHIBITORS | MAP3K5, MAP3K9, MAP4K2 | CYP1A2 1198/4885CYP2C19 658/4885MAPT 2476/4885 |
| US-11814444-B2 | Cyclic polypeptides for PCSK9 inhibition | PCSK9, LDLR, PCSK7 | CYP1A2 4606/4885CYP2C19 2639/4885MAPT 3313/4885 |
| US-20200123132-A1 | ANTIVIRAL COMPOUNDS | MAVS, EIF2AK2, ZC3HAV1 | CYP1A2 3826/4885CYP2C19 3298/4885MAPT 2923/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.