SCHEMBL2220503

SCHEMBL2220503

O=S(=O)(O)c1cc(Nc2nc(Cl)nc(Cl)n2)ccc1C=Cc1ccc(Nc2nc(Cl)nc(Cl)n2)cc1S(=O)(=O)O.[NaH]

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 2/20 0.48
CA12 O43570 6/20 0.47
CA1 P00915 6/20 0.47
CA2 P00918 6/20 0.47
CA9 Q16790 6/20 0.47
CA14 Q9ULX7 1/20 0.47
CHAT P28329 3/20 0.42
USP2 O75604 1/20 0.42
APEX1 P27695 1/20 0.42
HPGDS O60760 1/20 0.42
NFKB1 P19838 3/20 0.41
ENPP3 O14638 1/20 0.41
ENPP1 P22413 1/20 0.41
POLB P06746 1/20 0.40
TERT O14746 1/20 0.40
TXN P10599 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11732259 1.00 ENPP2 (0.48) ENPP2CA12CA1CA2CA9
SCHEMBL46608 0.99 ENPP2 (0.49) ENPP2CA12CA1CA2CA9
SCHEMBL2204687 0.99 ENPP2 (0.49) ENPP2CA12CA1CA2CA9
Calcium SCHEMBL2206379 0.97 ENPP2 (0.48) ENPP2CA12CA1CA2CA9
SCHEMBL2220482 0.96 ENPP2 (0.47) ENPP2CA12CA1CA2CA9
SCHEMBL16258799 0.94 ENPP2 (0.45) ENPP2CA12CA1CA2CA9
SCHEMBL2220496 0.93 CA12 (0.44) ENPP2CA12CA1CA2CA9
SCHEMBL16258775 0.92 ENPP2 (0.44) ENPP2CA12CA1CA2CA9
SCHEMBL11879462 0.91 CA12 (0.53) ENPP2CA12CA1CA2CA9
SCHEMBL4425719 0.91 CHAT (0.43) ENPP2CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2722190-B1 Optimized undercoat for thermal recording material RICOH IND FRANCE SAS (FR) 2015-12-16 EP disclosed
EP-2722190-A1 Optimized undercoat for thermal recording material Ricoh Industrie France SAS (FR) 2014-04-23 EP disclosed
US-8546300-B2 Thermosensitive recording material and image recording method RICOH COMPANY, LTD. (JP) 2013-10-01 US disclosed
US-20110177941-A1 THERMOSENSITIVE RECORDING MATERIAL AND IMAGE RECORDING METHOD RICOH COMPANY, LTD. (JP) 2011-07-21 US disclosed