Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 1/20 | 0.34 |
| ▸ | ATR | Q13535 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29499554 | 0.93 | SSTR4 (0.34) | SSTR4ATRSYK | |
| SCHEMBL26968131 | 0.93 | SSTR4 (0.34) | SSTR4ATRSYK | |
| SCHEMBL22207190 | 0.89 | SSTR4 (0.34) | SSTR4ATR | |
| SCHEMBL26968136 | 0.82 | SSTR4 (0.33) | SSTR4SYK | |
| SCHEMBL29499569 | 0.82 | SSTR4 (0.33) | SSTR4SYK | |
| SCHEMBL26968143 | 0.79 | SSTR4 (0.36) | SSTR4ATR | |
| SCHEMBL31027404 | 0.79 | ATR (0.48) | SSTR4ATRSYK | |
| SCHEMBL26985019 | 0.76 | SSTR4 (0.40) | SSTR4ATRSYK | |
| SCHEMBL22225026 | 0.74 | SSTR4 (0.40) | SSTR4ATRSYK | |
| SCHEMBL29499575 | 0.74 | SSTR4 (0.40) | SSTR4ATRSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3908579-B1 | DIHYDROOROTATE DEHYDROGENASE INHIBITORS | JANSSEN BIOTECH INC (US) | 2023-12-27 | — | — | EP | disclosed |
| EP-3908579-A1 | DIHYDROOROTATE DEHYDROGENASE INHIBITORS | Janssen Biotech, Inc. (US) | 2021-11-17 | — | — | EP | disclosed |
| WO-2020144638-A1 | DIHYDROOROTATE DEHYDROGENASE INHIBITORS | JANSSEN BIOTECH, INC. (US) | 2020-07-16 | — | — | WO | disclosed |