Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ASPH | Q12797 | 1/20 | 0.33 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26984974 | 0.93 | SSTR4 (0.43) | SSTR4ATRSYKBACE1BACE2 | |
| SCHEMBL31613428 | 0.82 | SSTR4 (0.41) | SSTR4KDM4EASPHKDM8ATR | |
| SCHEMBL18013606 | 0.81 | SSTR4 (0.42) | SSTR4ATRSYKBACE1BACE2 | |
| SCHEMBL3466985 | 0.79 | SSTR4 (0.36) | SSTR4ATRSYKUSP30TACR1 | |
| SCHEMBL26968143 | 0.78 | SSTR4 (0.36) | SSTR4KDM4EASPHKDM8ATR | |
| SCHEMBL29100813 | 0.78 | SSTR4 (0.44) | SSTR4ATRSYKBACE1BACE2 | |
| SCHEMBL26985281 | 0.77 | SSTR4 (0.35) | SSTR4 | |
| SCHEMBL22207282 | 0.76 | SSTR4 (0.34) | SSTR4ATRSYK | |
| SCHEMBL3467897 | 0.76 | SSTR4 (0.40) | SSTR4ATRSYKUSP30TACR1 | |
| SCHEMBL960537 | 0.76 | ATR (0.36) | SSTR4ATRSYKUSP30AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024010925-A2 | MITOGEN-ACTIVATED PROTEIN KINASE (MEK) INHIBITORS | NESTED THERAPEUTICS, INC. (US) | 2024-01-11 | — | — | WO | disclosed |