Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29499569 | 1.00 | SSTR4 (0.33) | SSTR4SYKUSP30 | |
| SCHEMBL22207190 | 0.94 | SSTR4 (0.34) | SSTR4 | |
| SCHEMBL26968131 | 0.88 | SSTR4 (0.34) | SSTR4SYKUSP30 | |
| SCHEMBL29499554 | 0.88 | SSTR4 (0.34) | SSTR4SYKUSP30 | |
| SCHEMBL22207282 | 0.82 | SSTR4 (0.34) | SSTR4SYK | |
| SCHEMBL22225026 | 0.79 | SSTR4 (0.40) | SSTR4SYKUSP30 | |
| SCHEMBL29499575 | 0.79 | SSTR4 (0.40) | SSTR4SYKUSP30 | |
| SCHEMBL29499559 | 0.76 | SSTR4 (0.36) | SSTR4SYKUSP30 | |
| SCHEMBL26968139 | 0.76 | SSTR4 (0.36) | SSTR4SYKUSP30 | |
| SCHEMBL3466985 | 0.73 | SSTR4 (0.36) | SSTR4SYKUSP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3908579-B1 | DIHYDROOROTATE DEHYDROGENASE INHIBITORS | JANSSEN BIOTECH INC (US) | 2023-12-27 | — | — | EP | disclosed |
| US-20220089568-A1 | DIHYDROOROTATE DEHYDROGENASE INHIBITORS | JANSSEN BIOTECH, INC. | 2022-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220089568-A1 | DIHYDROOROTATE DEHYDROGENASE INHIBITORS | DHODH, DLD, DPYD | SSTR4 4870/4885SYK 4630/4885USP30 2340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.