Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22481612 | 0.83 | PIN1 (0.73) | PIN1ALDH1A1L3MBTL1POLBATM | |
| SCHEMBL23928919 | 0.81 | PIN1 (1.00) | PIN1ALDH1A1L3MBTL1 | |
| SCHEMBL27246196 | 0.81 | PIN1 (1.00) | PIN1ALDH1A1L3MBTL1 | |
| SCHEMBL27246195 | 0.81 | PIN1 (1.00) | PIN1ALDH1A1L3MBTL1 | |
| SCHEMBL23961059 | 0.79 | PIN1 (0.67) | PIN1ALDH1A1L3MBTL1 | |
| SCHEMBL22481614 | 0.77 | PIN1 (0.64) | PIN1ALDH1A1L3MBTL1 | |
| SCHEMBL23928922 | 0.77 | PIN1 (0.63) | PIN1ALDH1A1L3MBTL1 | |
| SCHEMBL22481537 | 0.76 | PIN1 (0.63) | PIN1ALDH1A1L3MBTL1POLB | |
| SCHEMBL23928923 | 0.75 | PIN1 (0.62) | PIN1ALDH1A1L3MBTL1 | |
| SCHEMBL22481546 | 0.73 | PIN1 (0.59) | PIN1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113939285-B | Modulators of Pin1 activity and uses thereof | 耶达研究及发展有限公司 | 2024-11-01 | — | — | CN | disclosed |
| CN-113939285-A | Modulators of Pin1 activity and uses thereof | 耶达研究及发展有限公司 | 2022-01-14 | — | — | CN | disclosed |
| EP-3908268-A1 | MODULATORS OF PIN1 ACTIVITY AND USES THEREOF | Yeda Research and Development Co. Ltd (IL) | 2021-11-17 | — | — | EP | disclosed |
| US-20210332024-A1 | MODULATORS OF PIN1 ACTIVITY AND USES THEREOF | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2021-10-28 | — | — | US | disclosed |
| US-20210332024-A1 | MODULATORS OF PIN1 ACTIVITY AND USES THEREOF | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2021-10-28 | — | — | US | disclosed |
| WO-2020144695-A1 | MODULATORS OF PIN1 ACTIVITY AND USES THEREOF | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2020-07-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210332024-A1 | MODULATORS OF PIN1 ACTIVITY AND USES THEREOF | PIN1, CNKSR1, PPIL1 | PIN1 1/4885ALDH1A1 3322/4885L3MBTL1 563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.