SCHEMBL22207472

SCHEMBL22207472

C[SiH](C)Oc1[c]cccc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28686793 0.77
SCHEMBL94672 0.74
SCHEMBL7100899 0.73
SCHEMBL10395477 0.73 ALDH1A1 (0.42)
SCHEMBL1413 0.73
SCHEMBL329137 0.72
SCHEMBL152163 0.72 LTA4H (0.32)
SCHEMBL27842990 0.71
SCHEMBL10702137 0.71
SCHEMBL28313311 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240238188-A1 OILY COSMETIC SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-07-18 US disclosed
EP-4338726-A1 OILY COSMETIC SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-03-20 EP disclosed
US-20230172831-A1 COSMETIC SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-06-08 US disclosed
EP-4159278-A1 COSMETIC PREPARATAION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-04-05 EP disclosed
US-11389389-B2 Cosmetic SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-07-19 US disclosed
US-20200246246-A1 COSMETIC SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-08-06 US disclosed
WO-2020144978-A1 DISPERSIBLE POWDER AND COSMETIC 信越化学工業株式会社 2020-07-16 WO disclosed