Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.73 |
| ▸ | POLB | P06746 | 9/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.69 |
| ▸ | MEN1 | O00255 | 5/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.69 |
| ▸ | RECQL | P46063 | 3/20 | 0.69 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.69 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.69 |
| ▸ | NPC1 | O15118 | 1/20 | 0.69 |
| ▸ | RAB9A | P51151 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.64 |
| ▸ | CASP1 | P29466 | 1/20 | 0.64 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.64 |
| ▸ | BLM | P54132 | 1/20 | 0.64 |
| ▸ | CASP7 | P55210 | 1/20 | 0.64 |
| ▸ | PREP | P48147 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22207998 | 0.95 | HSD17B10 (0.68) | HSD17B10POLBKDM4EL3MBTL1MEN1 | |
| SCHEMBL28757725 | 0.87 | POLB (0.69) | HSD17B10POLBKDM4EL3MBTL1MEN1 | |
| SCHEMBL22374902 | 0.85 | HSD17B10 (0.77) | HSD17B10POLBKDM4EL3MBTL1MEN1 | |
| SCHEMBL22208019 | 0.84 | HSD17B10 (0.76) | HSD17B10POLBKDM4EL3MBTL1MEN1 | |
| SCHEMBL22207990 | 0.83 | POLB (0.69) | HSD17B10POLBKDM4EL3MBTL1MEN1 | |
| SCHEMBL22208011 | 0.83 | HSD17B10 (0.68) | HSD17B10POLBKDM4EL3MBTL1MEN1 | |
| SCHEMBL22208026 | 0.81 | HSD17B10 (0.65) | HSD17B10POLBKDM4EL3MBTL1MEN1 | |
| SCHEMBL2363298 | 0.81 | ALDH1A1 (0.72) | HSD17B10POLBKDM4EL3MBTL1MEN1 | |
| Water SCHEMBL3871916 | 0.79 | ALDH1A1 (0.70) | HSD17B10POLBKDM4EL3MBTL1MEN1 | |
| SCHEMBL30861620 | 0.79 | ALDH1A1 (0.70) | HSD17B10POLBKDM4EL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3908306-A1 | PHOSPHATASE BINDING COMPOUNDS AND METHODS OF USING SAME | Yale University (US) | 2021-11-17 | — | — | EP | disclosed |
| US-20200268897-A1 | Phosphatase Binding Compounds and Methods of Using Same | YALE UNIVERSITY | 2020-08-27 | — | — | US | disclosed |
| US-20200268897-A1 | Phosphatase Binding Compounds and Methods of Using Same | YALE UNIVERSITY | 2020-08-27 | — | — | US | disclosed |
| WO-2020146470-A1 | Phosphatase Binding Compounds and Methods of Using Same | YALE UNIVERSITY (US) | 2020-07-16 | — | — | WO | disclosed |
| WO-2020146470-A1 | Phosphatase Binding Compounds and Methods of Using Same | YALE UNIVERSITY (US) | 2020-07-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200268897-A1 | Phosphatase Binding Compounds and Methods of Using Same | PPP5C, PPP4C, DUSP26 | HSD17B10 2297/4885POLB 2253/4885KDM4E 2696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.