Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH2 | Q6NS38 | 2/20 | 0.63 |
| ▸ | HPGDS | O60760 | 1/20 | 0.63 |
| ▸ | EGLN1 | Q9GZT9 | 9/20 | 0.55 |
| ▸ | ALKBH1 | Q13686 | 8/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27835961 | 0.86 | ALKBH2 (0.45) | ALKBH2HPGDSEGLN1ALKBH1MAPK14 | |
| SCHEMBL14947694 | 0.86 | ALKBH2 (0.45) | ALKBH2HPGDSEGLN1ALKBH1MAPK14 | |
| SCHEMBL20263286 | 0.83 | ALKBH2 (0.43) | ALKBH2HPGDSEGLN1ALKBH1MAPK14 | |
| SCHEMBL26054428 | 0.82 | ALKBH2 (0.42) | ALKBH2HPGDSEGLN1ALKBH1MAPK14 | |
| SCHEMBL4647029 | 0.81 | ALKBH1 (0.56) | ALKBH2HPGDSEGLN1ALKBH1 | |
| SCHEMBL30529091 | 0.81 | ALKBH1 (0.56) | ALKBH2HPGDSEGLN1ALKBH1 | |
| SCHEMBL2861126 | 0.81 | ALKBH2 (0.63) | ALKBH2HPGDSEGLN1ALKBH1 | |
| SCHEMBL11480162 | 0.81 | ALKBH2 (0.63) | ALKBH2HPGDSEGLN1ALKBH1MAPK14 | |
| SCHEMBL22396399 | 0.80 | ALKBH2 (0.58) | ALKBH2HPGDSEGLN1ALKBH1 | |
| SCHEMBL14692557 | 0.79 | EGLN1 (0.53) | ALKBH2HPGDSEGLN1ALKBH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020146779-A1 | mTORC1 INHIBITORS FOR ACTIVATING AUTOPHAGY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-07-16 | — | — | WO | disclosed |
| WO-2020146779-A1 | mTORC1 INHIBITORS FOR ACTIVATING AUTOPHAGY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-07-16 | — | — | WO | disclosed |