Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 1/20 | 0.53 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22209763 | 0.82 | BPTF (0.46) | BPTFGPR119CHRNA7CHRNB2CHRNA4 | |
| SCHEMBL23951656 | 0.78 | BPTF (0.48) | BPTFGPR119CHRNA7CHRNB2CHRNA4 | |
| SCHEMBL15515714 | 0.73 | BPTF (0.63) | BPTFGPR119CHRNA7CHRNB2CHRNA4 | |
| SCHEMBL20858814 | 0.72 | BPTF (0.57) | BPTFCYP3A4HSD17B10NOTUMSIGMAR1 | |
| SCHEMBL18436512 | 0.71 | BPTF (0.50) | BPTFCHRNA7CHRNB2CHRNA4CYP3A4 | |
| SCHEMBL27318032 | 0.71 | BPTF (0.61) | BPTFMEN1KMT2ASMN1; SMN2NOTUM | |
| SCHEMBL18701824 | 0.70 | BPTF (0.46) | BPTFGPR119MAPK1MEN1KMT2A | |
| SCHEMBL19139371 | 0.70 | BPTF (0.54) | BPTFCHRNA7CHRNB2CHRNA4CYP3A4 | |
| SCHEMBL26496330 | 0.70 | BPTF (0.54) | BPTFCHRNA7CHRNB2CHRNA4CYP3A4 | |
| SCHEMBL10263800 | 0.69 | BPTF (1.00) | BPTFCHRNA7CHRNB2CHRNA4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10711004-B2 | Oxadiazole transient receptor potential channel inhibitors | GENENTECH, INC. (US) | 2020-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10711004-B2 | Oxadiazole transient receptor potential channel inhibitors | TRPA1, TRPV1, TRPV3 | BPTF 4510/4885GPR119 488/4885CHRNA7 670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.