SCHEMBL2221085

SCHEMBL2221085

CCCCCOCCCCCO

nearest known ligand 0.77

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.77
KMT2A Q03164 2/20 0.77
HTT P42858 2/20 0.77
THRB P10828 1/20 0.77
MAPT P10636 1/20 0.77
LMNA P02545 2/20 0.68
TSHR P16473 2/20 0.68
ALDH1A1 P00352 2/20 0.68
HSD17B10 Q99714 1/20 0.68
SMN1; SMN2 Q16637 1/20 0.63
USP2 O75604 1/20 0.54
CES2 O00748 1/20 0.52
ACHE P22303 6/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9646500 1.00 MEN1 (0.77) MEN1KMT2AHTTTHRBMAPT
SCHEMBL8956073 1.00 MEN1 (0.77) MEN1KMT2AHTTTHRBMAPT
SCHEMBL2527727 1.00 MEN1 (0.77) MEN1KMT2AHTTTHRBMAPT
SCHEMBL314263 1.00 MEN1 (0.77) MEN1KMT2AHTTTHRBMAPT
SCHEMBL23014943 1.00 MEN1 (0.77) MEN1KMT2AHTTTHRBMAPT
SCHEMBL23014835 1.00 MEN1 (0.77) MEN1KMT2AHTTTHRBMAPT
SCHEMBL139902 1.00 MEN1 (0.77) MEN1KMT2AHTTTHRBMAPT
SCHEMBL24304662 1.00 MEN1 (0.77) MEN1KMT2AHTTTHRBMAPT
SCHEMBL16815923 1.00 MEN1 (0.77) MEN1KMT2AHTTTHRBMAPT
SCHEMBL427999 1.00 MEN1 (0.77) MEN1KMT2AHTTTHRBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8461135-B2 Boron-containing small molecules as anti-inflammatory agents ANACOR PHARMACEUTICALS, INC. (US) 2013-06-11 US claimed
US-8039450-B2 Boron-containing small molecules as anti-inflammatory agents ANACOR PHARMACEUTICALS, INC. (US) 2011-10-18 US claimed
US-12034122-B2 Electrolytic solution for lithium-ion secondary battery and lithium-ion secondary battery MURATA MANUFACTURING CO., LTD. (JP) 2024-07-09 US disclosed
CN-112074983-B Electrolyte for lithium ion secondary battery and lithium ion secondary battery 株式会社村田制作所 2024-06-04 CN disclosed
EP-4374877-A2 PHARMACEUTICAL CONTAINING SODIUM-DEPENDENT PHOSPHATE TRANSPORTER INHIBITOR AND PHOSPHORUS ADSORBENT FOR USE IN THE PREVENTION, TREATMENT OR SUPPRESSION OF CHRONIC KIDNEY DISEASE, ARTERIOSCLEROSIS ASSOCIATED WITH VASCULAR CALCIFICATION, OR ECTOPIC CALCIFICATION. CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-05-29 EP disclosed
EP-3928779-B1 PHARMACEUTICAL CONTAINING SODIUM-DEPENDENT PHOSPHATE TRANSPORTER INHIBITOR AND PHOSPHORUS ADSORBENT FOR USE IN THE PREVENTION, TREATMENT OR SUPPRESSION OF CHRONIC KIDNEY DISEASE, ARTERIOSCLEROSIS ASSOCIATED WITH VASCULAR CALCIFICATION, OR ECTOPIC CALCIFICATION. CHUGAI PHARMACEUTICAL CO LTD (JP) 2024-03-06 EP disclosed
CN-112638477-B Pyrrolo [2,3-B ] pyridine derivatives as inhibitors of influenza virus replication 共晶制药公司 2024-01-26 CN disclosed
CN-110637022-B Pyrrolopyrimidine derivatives as inhibitors of influenza virus replication 共晶制药公司 2022-09-16 CN disclosed
EP-3928779-A1 PHARMACEUTICAL CONTAINING SODIUM-DEPENDENT PHOSPHATE TRANSPORTER INHIBITOR AND PHOSPHORUS ADSORBENT FOR USE IN THE PREVENTION, TREATMENT OR SUPPRESSION OF CHRONIC KIDNEY DISEASE, ARTERIOSCLEROSIS ASSOCIATED WITH VASCULAR CALCIFICATION, OR ECTOPIC CALCIFICATION. Chugai Seiyaku Kabushiki Kaisha (JP) 2021-12-29 EP disclosed
EP-3192511-B1 PHARMACEUTICAL CONTAINING SODIUM-DEPENDENT PHOSPHATE TRANSPORTER INHIBITOR CHUGAI PHARMACEUTICAL CO LTD (JP) 2021-07-14 EP disclosed
US-11014941-B2 Pyrrolopyrimidine derivatives useful as inhibitors of influenza virus replication COCRYSTAL PHARMA, INC. (US) 2021-05-25 US disclosed
US-5053514-A Side effect reduction; carbostyril derivatives OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1991-10-01 US disclosed
EP-0239129-B1 HYDROQUINOLINE COMPOUNDS, COMPOSITIONS CONTAINING SAME AND PROCESSES FOR PREPARING SAME OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1991-09-25 EP disclosed
US-5037827-A Useful for treatment of disease caused by platelet activating factory EISAI CO., LTD. (JP) 1991-08-06 US disclosed
EP-0411150-A1 INDOLE DERIVATIVES, PREPARATION THEREOF, AND DRUG FOR PREVENTING AND TREATING NEPHRITIS CONTAINING SAME OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1991-02-06 EP disclosed
US-4963566-A ANTIULCER AGENT OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1990-10-16 US disclosed
EP-0353474-A2 Glycerin derivative and its pharmacological use Eisai Co., Ltd. (JP) 1990-02-07 EP disclosed
CN-1039414-A Glycerol derivatives and pharmaceutical use thereof EISAI CO LTD (JP) 1990-02-07 CN disclosed
US-4743383-A ORGANOPHILIC CLAY, PREVENTION OF FLUID LOSS PHILLIPS PETROLEUM COMPANY (US) 1988-05-10 US disclosed
EP-0239129-A2 Hydroquinoline compounds, compositions containing same and processes for preparing same OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1987-09-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11014941-B2 Pyrrolopyrimidine derivatives useful as inhibitors of influenza virus replication ITPA, POLR2H, POLR2E MEN1 4650/4885KMT2A 2703/4885HTT 3679/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.