Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ECE1 | P42892 | 3/20 | 0.42 |
| ▸ | ACHE | P22303 | 8/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28514607 | 0.78 | HTT (0.42) | HTTECE1ACHEEPHX2PLA2G2A | |
| SCHEMBL9680064 | 0.78 | HTT (0.42) | HTTECE1ACHEEPHX2PLA2G2A | |
| SCHEMBL7348617 | 0.78 | HTT (0.42) | HTTECE1ACHEEPHX2PLA2G2A | |
| SCHEMBL7255174 | 0.78 | HDAC3 (0.46) | HTTECE1ACHEEPHX2L3MBTL1 | |
| SCHEMBL23077522 | 0.78 | ACHE (0.47) | HTTECE1ACHEEPHX2 | |
| SCHEMBL2220618 | 0.77 | EGLN1 (0.42) | HTTECE1ACHELMNAPLA2G2A | |
| Hydrochloric Acid SCHEMBL27336202 | 0.77 | HDAC3 (0.45) | HTTECE1ACHEEPHX2L3MBTL1 | |
| SCHEMBL9313040 | 0.75 | ACHE (0.42) | HTTECE1ACHEEPHX2 | |
| SCHEMBL22830086 | 0.75 | HTT (0.40) | HTTECE1ACHEEPHX2LMNA | |
| SCHEMBL205904 | 0.75 | EPHX1 (0.50) | HTTECE1LMNAPLA2G2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2521711-A1 | QUATERNARY AMMONIUM SALT PRODRUGS | Alkermes, Inc. (US) | 2012-11-14 | — | — | EP | disclosed |
| WO-2011084846-A1 | QUATERNARY AMMONIUM SALT PRODRUGS | ALKERMES, INC. (US) | 2011-07-14 | — | — | WO | disclosed |
| WO-2011084849-A1 | DIARYLDIAZEPINE PRODRUGS FOR THE TREATMENT OF NEUROLOGICAL AND PSYCHOLOGICAL DISORDERS | ALKERMES, INC. (US) | 2011-07-14 | — | — | WO | disclosed |