Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ECE1 | P42892 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 7/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15550570 | 0.88 | HTT (0.56) | HTTKMT2AACHEEPHX2PRMT1 | |
| SCHEMBL19513089 | 0.86 | PRMT1 (0.53) | HTTKMT2ATSHRACHEEPHX2 | |
| SCHEMBL9313040 | 0.83 | ACHE (0.42) | HTTECE1ACHEEPHX2BBOX1 | |
| SCHEMBL7769360 | 0.81 | ACHE (0.35) | HTTACHE | |
| SCHEMBL7769356 | 0.81 | ACHE (0.35) | HTTACHE | |
| SCHEMBL28514607 | 0.78 | HTT (0.42) | HTTECE1KMT2AACHEEPHX2 | |
| SCHEMBL2221096 | 0.78 | HTT (0.42) | HTTECE1KMT2AACHEEPHX2 | |
| SCHEMBL7255174 | 0.78 | HDAC3 (0.46) | HTTECE1KMT2AACHEEPHX2 | |
| SCHEMBL7348617 | 0.78 | HTT (0.42) | HTTECE1KMT2AACHEEPHX2 | |
| SCHEMBL9262629 | 0.78 | HTT (0.39) | HTTECE1KMT2AACHEEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2903979-B1 | NOVEL COMPOUNDS, THEIR PREPARATION AND THEIR USES | INHIBIKASE THERAPEUTICS INC (US) | 2020-08-19 | — | — | EP | claimed |
| EP-0272063-B1 | MITOMYCIN DERIVATIVES | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1992-04-08 | — | — | EP | disclosed |