Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PEPD | P12955 | 3/20 | 0.37 |
| ▸ | MMP2 | P08253 | 8/20 | 0.37 |
| ▸ | ANPEP | P15144 | 2/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | XPNPEP1 | Q9NQW7 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29142179 | 0.80 | POLB (0.36) | PEPDMMP2ANPEPPOLBDPP4 | |
| SCHEMBL29142178 | 0.80 | POLB (0.36) | PEPDMMP2ANPEPPOLBDPP4 | |
| SCHEMBL19143937 | 0.79 | — | — | |
| SCHEMBL10138946 | 0.77 | MMP2 (0.46) | PEPDMMP2ANPEPPOLBDPP4 | |
| SCHEMBL3012517 | 0.77 | PEPD (0.39) | PEPDMMP2ANPEPPOLBXPNPEP1 | |
| SCHEMBL22541600 | 0.76 | PEPD (0.36) | PEPDMMP2ANPEPPOLBXPNPEP1 | |
| SCHEMBL18084396 | 0.76 | PEPD (0.36) | PEPDMMP2ANPEPPOLBDPP4 | |
| SCHEMBL21199412 | 0.73 | PEPD (0.37) | PEPDMMP2ANPEPPOLBXPNPEP1 | |
| SCHEMBL32683359 | 0.72 | DPP4 (0.41) | PEPDMMP2ANPEPPOLBXPNPEP1 | |
| SCHEMBL1700706 | 0.72 | DPP4 (0.32) | PEPDMMP2POLBDPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2975030-B1 | DIHYDROPYRIDAZINE-3,5-DIONE DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2020-07-15 | — | — | EP | disclosed |